| Item Type | Name |
|
Concept
|
Adaptor Proteins, Signal Transducing
|
|
Concept
|
Receptors, Complement 3b
|
|
Concept
|
Nerve Growth Factor
|
|
Concept
|
Electrophoresis, Polyacrylamide Gel
|
|
Concept
|
Longitudinal Studies
|
|
Concept
|
Estradiol
|
|
Concept
|
Silver Staining
|
|
Concept
|
Vitamin B 6
|
|
Concept
|
Odds Ratio
|
|
Concept
|
Cerebral Amyloid Angiopathy
|
|
Concept
|
Cyclic AMP Response Element-Binding Protein
|
|
Concept
|
Parents
|
|
Concept
|
Fatal Outcome
|
|
Concept
|
Infarction
|
|
Concept
|
Glycogen Synthase Kinase 3
|
|
Concept
|
Gene Expression Regulation, Enzymologic
|
|
Concept
|
Cause of Death
|
|
Concept
|
Gene Expression Profiling
|
|
Concept
|
Markov Chains
|
|
Concept
|
Body Mass Index
|
|
Concept
|
Lupus Coagulation Inhibitor
|
|
Concept
|
Vascular Endothelial Growth Factor A
|
|
Concept
|
Insulin
|
|
Concept
|
Specimen Handling
|
|
Concept
|
Enzyme-Linked Immunosorbent Assay
|
|
Concept
|
Protein Binding
|
|
Concept
|
Age Factors
|
|
Concept
|
Disease Models, Animal
|
|
Concept
|
Fibroblasts
|
|
Concept
|
Lymphatic System
|
|
Concept
|
DNA Methylation
|
|
Concept
|
Health Surveys
|
|
Concept
|
Databases, Factual
|
|
Concept
|
Fatty Acids, Omega-6
|
|
Concept
|
DNA-Binding Proteins
|
|
Concept
|
Amyloid beta-Protein Precursor
|
|
Concept
|
Thiazoles
|
|
Concept
|
Imaging, Three-Dimensional
|
|
Concept
|
Blood-Brain Barrier
|
|
Concept
|
Vitamin K
|
|
Concept
|
Guidelines as Topic
|
|
Concept
|
Data Interpretation, Statistical
|
|
Concept
|
Blood Pressure
|
|
Concept
|
Protein Processing, Post-Translational
|
|
Concept
|
Genetic Association Studies
|
|
Concept
|
Interferon-gamma
|
|
Concept
|
alpha-Macroglobulins
|
|
Concept
|
Cerebral Infarction
|
|
Concept
|
Reactive Oxygen Species
|
|
Concept
|
Frontotemporal Lobar Degeneration
|
|
Concept
|
Pilot Projects
|
|
Concept
|
Triglycerides
|
|
Concept
|
Mutation
|
|
Concept
|
Humans
|
|
Concept
|
Health Literacy
|
|
Concept
|
Anthocyanins
|
|
Concept
|
Urinary Incontinence
|
|
Concept
|
Likelihood Functions
|
|
Concept
|
Sequence Analysis, RNA
|
|
Concept
|
Intracranial Arteriosclerosis
|
|
Concept
|
Fraud
|
|
Concept
|
Epigenomics
|
|
Concept
|
Pedigree
|
|
Concept
|
Lymphatic Vessels
|
|
Concept
|
Organ Size
|
|
Concept
|
Fatty Acids, Omega-3
|
|
Concept
|
Membrane Glycoproteins
|
|
Concept
|
Radionuclide Imaging
|
|
Concept
|
CpG Islands
|
|
Concept
|
Receptors, GABA
|
|
Concept
|
Down-Regulation
|
|
Concept
|
Gait
|
|
Concept
|
Chicago
|
|
Concept
|
Chromosomes, Human, Pair 18
|
|
Concept
|
Disability Evaluation
|
|
Concept
|
Epoxide Hydrolases
|
|
Concept
|
Bone Marrow
|
|
Concept
|
Food, Fortified
|
|
Concept
|
Multigene Family
|
|
Concept
|
alpha-Tocopherol
|
|
Concept
|
National Institute on Aging (U.S.)
|
|
Concept
|
Incidence
|
|
Concept
|
Introns
|
|
Concept
|
Proportional Hazards Models
|
|
Concept
|
Genes, Tumor Suppressor
|
|
Concept
|
Heterozygote
|
|
Concept
|
Insulin Receptor Substrate Proteins
|
|
Concept
|
Neurologic Examination
|
|
Concept
|
Epistasis, Genetic
|
|
Concept
|
Magnetic Resonance Imaging
|
|
Concept
|
Age of Onset
|
|
Concept
|
Preoptic Area
|
|
Concept
|
Phospholipase D
|
|
Concept
|
COS Cells
|
|
Concept
|
Illinois
|
|
Concept
|
Chi-Square Distribution
|
|
Concept
|
Quercetin
|
|
Concept
|
Depression
|
|
Concept
|
Geriatric Assessment
|
|
Concept
|
Diet Surveys
|
|
Concept
|
Antibodies, Antiphospholipid
|
|
Concept
|
Chromatin Immunoprecipitation
|
|
Concept
|
Molecular Biology
|
|
Concept
|
Confidence Intervals
|
|
Concept
|
Insulin-Like Growth Factor I
|
|
Concept
|
Genetic Testing
|
|
Concept
|
Algorithms
|
|
Concept
|
Mice, Knockout
|
|
Concept
|
Transcription Initiation Site
|
|
Concept
|
Statistics as Topic
|
|
Concept
|
Epidemiologic Studies
|
|
Concept
|
Carrier Proteins
|
|
Concept
|
Carbon Radioisotopes
|
|
Concept
|
Vitamin E
|
|
Concept
|
Insulin-Like Growth Factor Binding Protein 5
|
|
Concept
|
Child Development
|
|
Concept
|
GTP-Binding Proteins
|
|
Concept
|
HIV-1
|
|
Concept
|
Serpins
|
|
Concept
|
Trans Fatty Acids
|
|
Concept
|
Antibodies, Monoclonal
|
|
Concept
|
Cerebral Amyloid Angiopathy, Familial
|
|
Concept
|
Positron-Emission Tomography
|
|
Concept
|
Data Collection
|
|
Concept
|
Epigenesis, Genetic
|
|
Concept
|
ATP-Binding Cassette Transporters
|
|
Concept
|
Arthritis, Rheumatoid
|
|
Concept
|
Sex Factors
|
|
Concept
|
Analysis of Variance
|
|
Concept
|
Ethylene Glycols
|
|
Concept
|
Neuroimaging
|
|
Concept
|
Reverse Transcriptase Polymerase Chain Reaction
|
|
Concept
|
Feeding Behavior
|
|
Concept
|
Atherosclerosis
|
|
Concept
|
Nerve Growth Factors
|
|
Concept
|
Diffusion Magnetic Resonance Imaging
|
|
Concept
|
Phosphatidylserines
|
|
Concept
|
Epidemiologic Research Design
|
|
Concept
|
Cerebrovascular Circulation
|
|
Concept
|
Alzheimer Disease
|
|
Concept
|
Leukocytes, Mononuclear
|
|
Concept
|
Entorhinal Cortex
|
|
Concept
|
Genome, Human
|
|
Concept
|
Medicare
|
|
Concept
|
Amyloid Precursor Protein Secretases
|
|
Concept
|
Cognitive Reserve
|
|
Concept
|
Genotype
|
|
Concept
|
Chromosomes, Human, Pair 3
|
|
Concept
|
Polymorphism, Genetic
|
|
Concept
|
Child Abuse
|
|
Concept
|
Metabolic Clearance Rate
|
|
Concept
|
Gray Matter
|
|
Concept
|
B-Lymphocyte Subsets
|
|
Concept
|
Fluorescent Antibody Technique
|
|
Concept
|
Mitogen-Activated Protein Kinase Kinases
|
|
Concept
|
Endothelium, Vascular
|
|
Concept
|
Practice Guidelines as Topic
|
|
Concept
|
PrPC Proteins
|
|
Concept
|
Transcriptome
|
|
Concept
|
Plaque, Amyloid
|
|
Concept
|
Long-Term Potentiation
|
|
Concept
|
Treatment Outcome
|
|
Concept
|
Mice, Inbred BALB C
|
|
Concept
|
Sensitivity and Specificity
|
|
Concept
|
HSP70 Heat-Shock Proteins
|
|
Concept
|
Protective Factors
|
|
Concept
|
Bromine
|
|
Concept
|
Microscopy, Electron, Transmission
|
|
Concept
|
Cerebral Arterial Diseases
|
|
Concept
|
Dietary Fats
|
|
Concept
|
Flavonols
|
|
Concept
|
Single-Blind Method
|
|
Concept
|
Polymorphism, Single Nucleotide
|
|
Concept
|
Cohort Studies
|
|
Concept
|
Seasons
|
|
Concept
|
Integrin alphaVbeta3
|
|
Concept
|
Databases, Genetic
|
|
Concept
|
Stroke
|
|
Concept
|
Mortality
|
|
Concept
|
Vitamin B 12
|
|
Concept
|
Unconsciousness
|
|
Concept
|
Image Interpretation, Computer-Assisted
|
|
Concept
|
Antibodies, Viral
|
|
Concept
|
Blotting, Western
|
|
Concept
|
Tuberous Sclerosis
|
|
Concept
|
Quantitative Trait Loci
|
|
Concept
|
Atrophy
|
|
Concept
|
Transcription Factors
|
|
Concept
|
Dementia
|
|
Concept
|
High-Throughput Nucleotide Sequencing
|
|
Concept
|
Gene Library
|
|
Concept
|
National Institute of Neurological Disorders and Stroke (U.S.)
|
|
Concept
|
Peptidylprolyl Isomerase
|
|
Concept
|
Prevalence
|
|
Concept
|
Case-Control Studies
|
|
Concept
|
Lewy Body Disease
|
|
Concept
|
Microcirculation
|
|
Concept
|
Dura Mater
|
|
Concept
|
Predictive Value of Tests
|
|
Concept
|
Reproducibility of Results
|
|
Concept
|
CD4-Positive T-Lymphocytes
|
|
Concept
|
Prospective Studies
|
|
Concept
|
Cross-Sectional Studies
|
|
Concept
|
Rats
|
|
Concept
|
Socioeconomic Factors
|
|
Concept
|
Chromosome Mapping
|
|
Concept
|
Autoradiography
|
|
Concept
|
Decision Making
|
|
Concept
|
Hemoglobins
|
|
Concept
|
False Positive Reactions
|
|
Concept
|
Cost of Illness
|
|
Concept
|
Choice Behavior
|
|
Concept
|
Genome-Wide Association Study
|
|
Concept
|
Alternative Splicing
|
|
Concept
|
Multiple Sclerosis
|
|
Concept
|
Proteomics
|
|
Concept
|
Circle of Willis
|
|
Concept
|
Surveys and Questionnaires
|
|
Concept
|
Tomography, X-Ray Computed
|
|
Concept
|
CA2 Region, Hippocampal
|
|
Concept
|
Housing for the Elderly
|
|
Concept
|
Vasoactive Intestinal Peptide
|
|
Concept
|
Walking
|
|
Concept
|
Aspartic Acid Endopeptidases
|
|
Concept
|
B-Lymphocytes
|
|
Concept
|
Practice Patterns, Physicians'
|
|
Concept
|
Regression Analysis
|
|
Concept
|
Antigens, Differentiation, Myelomonocytic
|
|
Concept
|
Exome
|
|
Concept
|
Diabetes Mellitus
|
|
Concept
|
Frontotemporal Dementia
|
|
Concept
|
Genetic Predisposition to Disease
|
|
Concept
|
Renin-Angiotensin System
|
|
Concept
|
CA3 Region, Hippocampal
|
|
Concept
|
Genetic Loci
|
|
Concept
|
Longevity
|
|
Concept
|
T-Lymphocyte Subsets
|
|
Concept
|
Hydroxymethylglutaryl-CoA Reductase Inhibitors
|
|
Concept
|
HLA-D Antigens
|
|
Concept
|
Immunoglobulins
|
|
Concept
|
Antibodies, Monoclonal, Humanized
|
|
Concept
|
Protein Tyrosine Phosphatase, Non-Receptor Type 11
|
|
Concept
|
Dietary Supplements
|
|
Concept
|
Genome
|
|
Concept
|
Up-Regulation
|
|
Concept
|
Causality
|
|
Concept
|
National Heart, Lung, and Blood Institute (U.S.)
|
|
Concept
|
Arterial Pressure
|
|
Concept
|
Logistic Models
|
|
Concept
|
Homozygote
|
|
Concept
|
Chromatin
|
|
Concept
|
Cerebrovascular Disorders
|
|
Concept
|
Chromosomes, Human, Pair 7
|
|
Concept
|
Mice
|
|
Concept
|
Language
|
|
Concept
|
Cerebral Small Vessel Diseases
|
|
Concept
|
Clinical Trials as Topic
|
|
Concept
|
Aging
|
|
Concept
|
Factor Analysis, Statistical
|
|
Concept
|
Image Enhancement
|
|
Concept
|
Genetic Variation
|
|
Concept
|
Vascular Endothelial Growth Factors
|
|
Concept
|
Insulin Resistance
|
|
Concept
|
Cerebrovascular Trauma
|
|
Concept
|
Neprilysin
|
|
Concept
|
Statistics, Nonparametric
|
|
Concept
|
Olfactory Bulb
|
|
Concept
|
Consciousness Disorders
|
|
Concept
|
Hand Strength
|
|
Concept
|
Linear Models
|
|
Concept
|
GPI-Linked Proteins
|
|
Concept
|
Mutation Rate
|
|
Concept
|
Gene Frequency
|
|
Concept
|
Fluorine Radioisotopes
|
|
Concept
|
Fruit
|
|
Concept
|
Databases as Topic
|
|
Concept
|
Rats, Sprague-Dawley
|
|
Concept
|
Hippocampus
|
|
Concept
|
Probability
|
|
Concept
|
Off-Label Use
|
|
Concept
|
United States Food and Drug Administration
|
|
Concept
|
Gene Deletion
|
|
Concept
|
Risk Assessment
|
|
Concept
|
Estrogen Receptor beta
|
|
Concept
|
Neovascularization, Physiologic
|
|
Concept
|
Actigraphy
|
|
Concept
|
PubMed
|
|
Concept
|
Mutation, Missense
|
|
Concept
|
Risk
|
|
Concept
|
MicroRNAs
|
|
Concept
|
Risk Factors
|
|
Concept
|
Brain Infarction
|
|
Concept
|
Infarction, Middle Cerebral Artery
|
|
Concept
|
Dextrans
|
|
Concept
|
Vitamins
|
|
Concept
|
Dementia, Vascular
|
|
Concept
|
Alleles
|
|
Concept
|
Follow-Up Studies
|
|
Concept
|
Autopsy
|
|
Concept
|
Amyloid beta-Peptides
|
|
Concept
|
Receptors, Estrogen
|
|
Concept
|
Community Health Planning
|
|
Concept
|
Immunohistochemistry
|
|
Concept
|
Comorbidity
|
|
Concept
|
ROC Curve
|
|
Concept
|
Transcription Factor RelA
|
|
Concept
|
Brain-Derived Neurotrophic Factor
|
|
Concept
|
beta 2-Glycoprotein I
|
|
Concept
|
Hormone Replacement Therapy
|
|
Concept
|
Haplotypes
|
|
Concept
|
Cerebral Hemorrhage
|
|
Concept
|
Rats, Long-Evans
|
|
Concept
|
gamma-Tocopherol
|
|
Concept
|
Seafood
|
|
Concept
|
Mice, Inbred C57BL
|
|
Concept
|
Chromosomes, Human, Pair 9
|
|
Concept
|
Retrospective Studies
|
|
Concept
|
Phospholipase C gamma
|
|
Concept
|
Gene Expression Regulation
|
|
Concept
|
Computational Biology
|
|
Concept
|
Models, Statistical
|
|
Concept
|
Sialic Acid Binding Ig-like Lectin 3
|
|
Concept
|
Brain Mapping
|
|
Concept
|
Kaempferols
|
|
Concept
|
Mice, Transgenic
|
|
Concept
|
Vitamin B Complex
|
|
Concept
|
T-Lymphocytes
|
|
Concept
|
Fas-Associated Death Domain Protein
|
|
Concept
|
Decision Support Techniques
|
|
Concept
|
Cerebral Angiography
|
|
Concept
|
Phosphopyruvate Hydratase
|
|
Concept
|
Antigens, CD
|
|
Concept
|
Homocysteine
|
|
Concept
|
Monocytes
|
|
Concept
|
Drosophila
|
|
Concept
|
Diet Records
|
|
Concept
|
E2F Transcription Factors
|
|
Concept
|
DNA Mutational Analysis
|
|
Concept
|
Suprachiasmatic Nucleus
|
|
Concept
|
Exercise
|
|
Concept
|
Exonucleases
|
|
Concept
|
Linkage Disequilibrium
|
|
Concept
|
Phenanthrolines
|
|
Concept
|
Severity of Illness Index
|
|
Concept
|
Time Factors
|
|
Concept
|
Gene Dosage
|
|
Concept
|
Cell Count
|
|
Concept
|
Mendelian Randomization Analysis
|
|
Concept
|
Estrogen Receptor alpha
|
|
Concept
|
Cholesterol Ester Transfer Proteins
|
|
Concept
|
Glucose
|
|
Concept
|
HLA-DRB5 Chains
|
|
Academic Article
|
Cerebrovascular disease pathology and parkinsonian signs in old age.
|
|
Academic Article
|
Cerebral amyloid angiopathy pathology and cognitive domains in older persons.
|
|
Academic Article
|
Chronic psychological distress and risk of Alzheimer's disease in old age.
|
|
Academic Article
|
Estimation of the mediation effect with a binary mediator.
|
|
Academic Article
|
TDP-43 pathology, cognitive decline, and dementia in old age.
|
|
Academic Article
|
Thoughts on B-vitamins and dementia.
|
|
Academic Article
|
Correlation of Alzheimer disease neuropathologic changes with cognitive status: a review of the literature.
|
|
Academic Article
|
Participation in cognitively stimulating activities and risk of incident Alzheimer disease.
|
|
Academic Article
|
Dietary folate and vitamin B12 intake and cognitive decline among community-dwelling older persons.
|
|
Academic Article
|
Rarity of the Alzheimer disease-protective APP A673T variant in the United States.
|
|
Academic Article
|
Vascular contributions to cognitive impairment and dementia: a statement for healthcare professionals from the american heart association/american stroke association.
|
|
Academic Article
|
Conscientiousness and the incidence of Alzheimer disease and mild cognitive impairment.
|
|
Academic Article
|
Novel late-onset Alzheimer disease loci variants associate with brain gene expression.
|
|
Academic Article
|
Alzheimer's disease: early alterations in brain DNA methylation at ANK1, BIN1, RHBDF2 and other loci.
|
|
Academic Article
|
Cognitive impairment, decline and fluctuations in older community-dwelling subjects with Lewy bodies.
|
|
Academic Article
|
Hippocampal sclerosis and TDP-43 pathology in aging and Alzheimer disease.
|
|
Academic Article
|
The TMEM106B locus and TDP-43 pathology in older persons without FTLD.
|
|
Academic Article
|
Relation of DASH- and Mediterranean-like dietary patterns to cognitive decline in older persons.
|
|
Academic Article
|
Cellular, synaptic, and biochemical features of resilient cognition in Alzheimer's disease.
|
|
Academic Article
|
Ex vivo T2 relaxation: associations with age-related neuropathology and cognition.
|
|
Academic Article
|
Mixed pathology is more likely in black than white decedents with Alzheimer dementia.
|
|
Academic Article
|
Use of florbetapir-PET for imaging beta-amyloid pathology.
|
|
Academic Article
|
Association of brain pathology with the progression of frailty in older adults.
|
|
Academic Article
|
Alzheimer's loci: epigenetic associations and interaction with genetic factors.
|
|
Academic Article
|
Effects of multiple genetic loci on age at onset in late-onset Alzheimer disease: a genome-wide association study.
|
|
Academic Article
|
Effect of common neuropathologies on progression of late life cognitive impairment.
|
|
Academic Article
|
Lewy bodies and olfactory dysfunction in old age.
|
|
Academic Article
|
Common variants at 7p21 are associated with frontotemporal lobar degeneration with TDP-43 inclusions.
|
|
Academic Article
|
Association of Seafood Consumption, Brain Mercury Level, and APOE e4 Status With Brain Neuropathology in Older Adults.
|
|
Academic Article
|
TDP-43 in familial and sporadic frontotemporal lobar degeneration with ubiquitin inclusions.
|
|
Academic Article
|
Disentangling the effects of age and APOE on neuropathology and late life cognitive decline.
|
|
Academic Article
|
Loneliness and risk of Alzheimer disease.
|
|
Academic Article
|
The relation of cigarette smoking to incident Alzheimer's disease in a biracial urban community population.
|
|
Academic Article
|
Association of lower hemoglobin level and neuropathology in community-dwelling older persons.
|
|
Academic Article
|
Soluble a-synuclein is a novel modulator of Alzheimer's disease pathophysiology.
|
|
Academic Article
|
Association of Parkinson disease risk loci with mild parkinsonian signs in older persons.
|
|
Academic Article
|
Relation of genomic variants for Alzheimer disease dementia to common neuropathologies.
|
|
Academic Article
|
Characteristics of MR infarcts associated with dementia and cognitive function in the elderly.
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The Rush Memory and Aging Project: study design and baseline characteristics of the study cohort.
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Demonstrated brain insulin resistance in Alzheimer's disease patients is associated with IGF-1 resistance, IRS-1 dysregulation, and cognitive decline.
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Olfactory identification and incidence of mild cognitive impairment in older age.
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The complex PrP(c)-Fyn couples human oligomeric A? with pathological tau changes in Alzheimer's disease.
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Selected findings from the Religious Orders Study and Rush Memory and Aging Project.
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Suprachiasmatic neuron numbers and rest-activity circadian rhythms in older humans.
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National Institute on Aging-Alzheimer's Association guidelines for the neuropathologic assessment of Alzheimer's disease: a practical approach.
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GBA mutations increase risk for Lewy body disease with and without Alzheimer disease pathology.
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Ex vivo MR volumetry of human brain hemispheres.
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Parkinsonism in Older Adults and Its Association With Adverse Health Outcomes and Neuropathology.
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Cerebrovascular and microglial states are not altered by functional neuroinflammatory gene variant.
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Temporal course of neurodegenerative effects on cognition in old age.
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Neurofibrillary tangles mediate the association of amyloid load with clinical Alzheimer disease and level of cognitive function.
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Positive florbetapir PET amyloid imaging in a subject with frequent cortical neuritic plaques and frontotemporal lobar degeneration with TDP43-positive inclusions.
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CR1 is associated with amyloid plaque burden and age-related cognitive decline.
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Locus coeruleus neuron density and parkinsonism in older adults without Parkinson's disease.
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Higher brain BDNF gene expression is associated with slower cognitive decline in older adults.
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Interaction of transactive response DNA binding protein 43 with nuclear factor ?B in mild cognitive impairment with episodic memory deficits.
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APOE e4 increases risk for dementia in pure synucleinopathies.
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Brain tocopherols related to Alzheimer's disease neuropathology in humans.
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Residual decline in cognition after adjustment for common neuropathologic conditions.
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Antemortem amyloid imaging and ?-amyloid pathology in a case with dementia with Lewy bodies.
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Temporal course and pathologic basis of unawareness of memory loss in dementia.
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Cognitive performance correlates with cortical isopeptide immunoreactivity as well as Alzheimer type pathology.
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Racial Differences in Cognitive Function and Risk of Incident Stroke.
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B-lymphocyte-mediated delayed cognitive impairment following stroke.
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Cognitive and social lifestyle: links with neuropathology and cognition in late life.
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A 2-process model for neuropathology of Alzheimer's disease.
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Parkinsonian signs and functional disability in old age.
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Sex differences in the clinical manifestations of Alzheimer disease pathology.
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Cerebral infarctions and the likelihood of dementia from Alzheimer disease pathology.
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Age at surgical menopause influences cognitive decline and Alzheimer pathology in older women.
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Associations of cerebrovascular and Alzheimer's disease pathology with brain atrophy.
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Life-span cognitive activity, neuropathologic burden, and cognitive aging.
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Harm avoidance and cerebral infarction.
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Dementia from Alzheimer disease and mixed pathologies in the oldest old.
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Brain microbleeds and cognitive function.
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Where vascular meets neurodegenerative disease.
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Association of DNA methylation in the brain with age in older persons is confounded by common neuropathologies.
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A novel GRN mutation (GRN c.708+6_+9delTGAG) in frontotemporal lobar degeneration with TDP-43-positive inclusions: clinicopathologic report of 6 cases.
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High blood pressure and microinfarcts: a link between vascular risk factors, dementia, and clinical Alzheimer's disease.
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APOE and cerebral amyloid angiopathy in community-dwelling older persons.
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The Role of MAPT Haplotype H2 and Isoform 1N/4R in Parkinsonism of Older Adults.
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Association of APOE with tau-tangle pathology with and without ?-amyloid.
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CD33 Alzheimer's disease locus: altered monocyte function and amyloid biology.
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The apolipoprotein E epsilon4 allele increases the odds of chronic cerebral infarction [corrected] detected at autopsy in older persons.
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Parkinsonianlike signs and risk of incident Alzheimer disease in older persons.
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Neuropathological associates of multiple cognitive functions in two community-based cohorts of older adults.
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Physical frailty in older persons is associated with Alzheimer disease pathology.
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The effect of social networks on the relation between Alzheimer's disease pathology and level of cognitive function in old people: a longitudinal cohort study.
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The CETP I405V polymorphism is associated with an increased risk of Alzheimer's disease.
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Overview and findings from the religious orders study.
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Neuropathologic correlates of regional brain volumes in a community cohort of older adults.
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Vulnerability to stress, anxiety, and development of dementia in old age.
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Cognitive activities during adulthood are more important than education in building reserve.
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Late-Life Vascular Risk Factors and Alzheimer Disease Neuropathology in Individuals with Normal Cognition.
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Ex vivo MRI transverse relaxation in community based older persons with and without Alzheimer's dementia.
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TDP-43 stage, mixed pathologies, and clinical Alzheimer's-type dementia.
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Diabetes, Hemoglobin A1C, and Regional Alzheimer Disease and Infarct Pathology.
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Role of APOE e4 Allele and Incident Stroke on Cognitive Decline and Mortality.
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Presynaptic proteins complexin-I and complexin-II differentially influence cognitive function in early and late stages of Alzheimer's disease.
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Urinary Incontinence, Incident Parkinsonism, and Parkinson's Disease Pathology in Older Adults.
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Genetic epistasis regulates amyloid deposition in resilient aging.
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Selective lowering of synapsins induced by oligomeric a-synuclein exacerbates memory deficits.
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Detection, risk factors, and functional consequences of cerebral microinfarcts.
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Age and the association of dementia-related pathology with trajectories of cognitive decline.
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Sleep fragmentation and Parkinson's disease pathology in older adults without Parkinson's disease.
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Association Between Brain Gene Expression, DNA Methylation, and Alteration of Ex Vivo Magnetic Resonance Imaging Transverse Relaxation in Late-Life Cognitive Decline.
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Genetic influence of plasma homocysteine on Alzheimer's disease.
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Financial and Health Literacy Predict Incident Alzheimer's Disease Dementia and Pathology.
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Vascular cognitive impairment.
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Frontotemporal dysregulation of the SNARE protein interactome is associated with faster cognitive decline in old age.
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Neurodegenerative disease and cognitive retest learning.
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TDP-43 pathology in anterior temporal pole cortex in aging and Alzheimer's disease.
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APOE e2e4 genotype, incident AD and MCI, cognitive decline, and AD pathology in older adults.
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Sex-Specific Association of Apolipoprotein E With Cerebrospinal Fluid Levels of Tau.
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Targeted brain proteomics uncover multiple pathways to Alzheimer's dementia.
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Sex-specific genetic predictors of Alzheimer's disease biomarkers.
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Late-life blood pressure association with cerebrovascular and Alzheimer disease pathology.
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Polygenic analysis of inflammatory disease variants and effects on microglia in the aging brain.
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Reproductive period and epigenetic modifications of the oxidative phosphorylation pathway in the human prefrontal cortex.
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A multi-omic atlas of the human frontal cortex for aging and Alzheimer's disease research.
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Evaluation of TDP-43 proteinopathy and hippocampal sclerosis in relation to APOE e4 haplotype status: a community-based cohort study.
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The human brainome: network analysis identifies HSPA2 as a novel Alzheimer’s disease target.
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Seasonal plasticity of cognition and related biological measures in adults with and without Alzheimer disease: Analysis of multiple cohorts.
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APOE genotypes as a risk factor for age-dependent accumulation of cerebrovascular disease in older adults.
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Sex differences in Alzheimer's disease and common neuropathologies of aging.
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Military-related risk factors for dementia.
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Attributable risk of Alzheimer's dementia attributed to age-related neuropathologies.
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Spinal motor neurons and motor function in older adults.
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In vivo hippocampal subfield shape related to TDP-43, amyloid beta, and tau pathologies.
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Epigenome-wide study uncovers large-scale changes in histone acetylation driven by tau pathology in aging and Alzheimer's human brains.
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Cognitive decline after elective and nonelective hospitalizations in older adults.
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Vascular dysfunction-The disregarded partner of Alzheimer's disease.
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Physical activity, common brain pathologies, and cognition in community-dwelling older adults.
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Postmortem neurodegenerative markers and trajectories of decline in cognitive systems.
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Neuropathological correlates and genetic architecture of microglial activation in elderly human brain.
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Education and cognitive reserve in old age.
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Brain iron is associated with accelerated cognitive decline in people with Alzheimer pathology.
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Associations of amygdala volume and shape with transactive response DNA-binding protein 43 (TDP-43) pathology in a community cohort of older adults.
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The time for multiple biomarkers in studies of cognitive aging and dementia is now.
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Genetic meta-analysis of diagnosed Alzheimer's disease identifies new risk loci and implicates A?, tau, immunity and lipid processing.
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Beta-amyloid pathology in human brain microvessel extracts from the parietal cortex: relation with cerebral amyloid angiopathy and Alzheimer's disease.
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Risk Aversion and Alzheimer Disease in Old Age.
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Progressive parkinsonism in older adults is related to the burden of mixed brain pathologies.
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Scam Awareness Related to Incident Alzheimer Dementia and Mild Cognitive Impairment: A Prospective Cohort Study.
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Association of Cortical ?-Amyloid Protein in the Absence of Insoluble Deposits With Alzheimer Disease.
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White matter hyperintensities in vascular contributions to cognitive impairment and dementia (VCID): Knowledge gaps and opportunities.
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Limbic-predominant age-related TDP-43 encephalopathy (LATE): consensus working group report.
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Antiphospholipid Antibodies: Cognitive and Motor Decline, Neuroimaging and Neuropathology.
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Sex differences in mixed neuropathologies in community-dwelling older adults.
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Neurofibrillary Tangles and Conversion to Mild Cognitive Impairment with Certain Antihypertensives.
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Tau interacts with SHP2 in neuronal systems and in Alzheimer's disease brains.
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Brain expression of the vascular endothelial growth factor gene family in cognitive aging and alzheimer's disease.
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Reply: Limbic-predominant age-related TDP-43 encephalopathy (LATE).
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Vascular Cognitive Impairment and?Dementia: JACC Scientific Expert Panel.
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Reply: LATE to the PART-y.
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Association of TDP-43 Pathology With Domain-specific Literacy in Older Persons.
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Alzheimer's disease frequency peaks in the tenth decade and is lower afterwards.
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Multiple Pathologic Pathways to Dementia in Football Players With Chronic Traumatic Encephalopathy.
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Cognition may link cortical IGFBP5 levels with motor function in older adults.
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Author Correction: Genetic meta-analysis of diagnosed Alzheimer's disease identifies new risk loci and implicates A?, tau, immunity and lipid processing.
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Microstructural changes in the brain mediate the association of AK4, IGFBP5, HSPB2, and ITPK1 with cognitive decline.
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Sex differences in the genetic predictors of Alzheimer's pathology.
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Advancing diagnostic criteria for sporadic cerebral amyloid angiopathy: Study protocol for a multicenter MRI-pathology validation of Boston criteria v2.0.
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Neocortical Lewy bodies are associated with impaired odor identification in community-dwelling elders without clinical PD.
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Common age-related neuropathologies and yearly variability in cognition.
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Hospitalization, Alzheimer's Disease and Related Neuropathologies, and Cognitive Decline.
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The synaptic pathology of cognitive life?.
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Contribution of TDP and hippocampal sclerosis to hippocampal volume loss in older-old persons.
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Brain Bromine Levels Associated with Alzheimer's Disease Neuropathology.
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Neuropathologic Correlates of White Matter Hyperintensities in a Community-Based Cohort of Older Adults.
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APOE e4-specific associations of VEGF gene family expression with cognitive aging and Alzheimer's disease.
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Research momentum brings hope for dementia in 2019.
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Sleep fragmentation, microglial aging, and cognitive impairment in adults with and without Alzheimer's dementia.
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Late-life cognitive decline is associated with hippocampal volume, above and beyond its associations with traditional neuropathologic indices.
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Human and mouse single-nucleus transcriptomics reveal TREM2-dependent and TREM2-independent cellular responses in Alzheimer's disease.
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Exceptionally low likelihood of Alzheimer's dementia in APOE2 homozygotes from a 5,000-person neuropathological study.
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A Clinicopathological Report of a 93-Year-Old Former Street Boxer With Coexistence of Chronic Traumatic Encephalopathy, Alzheimer's Disease, Dementia With Lewy Bodies, and Hippocampal Sclerosis With TDP-43 Pathology.
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Total daily physical activity, brain pathologies, and parkinsonism in older adults.
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Author Correction: Human and mouse single-nucleus transcriptomics reveal TREM2-dependent and TREM2-independent cellular responses in Alzheimer's disease.
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Academic Article
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Shared proteomic effects of cerebral atherosclerosis and Alzheimer's disease on the human brain.
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Scientific Advising and Reviewing: On strengthening the bond between the Alzheimer's Association and the scientific community.
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Genome-wide interaction analysis of pathological hallmarks in Alzheimer's disease.
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Limbic-predominant Age-related TDP-43 Encephalopathy and Distinct Longitudinal Profiles of Domain-specific Literacy.
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Genetics of Gene Expression in the Aging Human Brain Reveal TDP-43 Proteinopathy Pathophysiology.
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Academic Article
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Brain Insulin Signaling, Alzheimer Disease Pathology, and Cognitive Function.
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Association of Early-Life Cognitive Enrichment With Alzheimer Disease Pathological Changes and Cognitive Decline.
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Academic Article
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Publisher Correction: Shared proteomic effects of cerebral atherosclerosis and Alzheimer's disease on the human brain.
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Academic Article
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Cortical Proteins Associated With Cognitive Resilience in Community-Dwelling Older Persons.
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Academic Article
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What HIV in the Brain Can Teach Us About SARS-CoV-2 Neurological Complications?
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Academic Article
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Person-Specific Contributions of Brain Pathologies to Progressive Parkinsonism in Older Adults.
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Brain ?-Tocopherol Levels Are Associated with Presynaptic Protein Levels in Elderly Human Midfrontal Cortex.
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Academic Article
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Limbic-predominant age-related TDP-43 encephalopathy, ADNC pathology, and cognitive decline in aging.
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Academic Article
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Neuropathologic and Cognitive Correlates of Enlarged Perivascular Spaces in a Community-Based Cohort of Older Adults.
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Academic Article
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Limbic-predominant age-related TDP-43 encephalopathy in Black and White decedents.
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Academic Article
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Genetic variants and functional pathways associated with resilience to Alzheimer's disease.
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Academic Article
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A novel SNCA E83Q mutation in a case of dementia with Lewy bodies and atypical frontotemporal lobar degeneration.
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Academic Article
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Brain pathologies are associated with both the rate and variability of declining motor function in older adults.
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Academic Article
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Deconvolving the contributions of cell-type heterogeneity on cortical gene expression.
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Brain tocopherol levels are associated with lower activated microglia density in elderly human cortex.
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Cross-Species Analyses Identify Dlgap2 as a Regulator of Age-Related Cognitive Decline and Alzheimer's Dementia.
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Risk of Transmissibility From Neurodegenerative Disease-Associated Proteins: Experimental Knowns and Unknowns.
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Common Brain Structural Alterations Associated with Cardiovascular Disease Risk Factors and Alzheimer's Dementia: Future Directions and Implications.
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Brain arteriolosclerosis.
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Association of serial position scores on memory tests and hippocampal-related neuropathologic outcomes.
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Dietary carotenoids related to risk of incident Alzheimer dementia (AD) and brain AD neuropathology: a community-based cohort of older adults.
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Association of Low Systolic Blood Pressure with Postmortem Amyloid-? and Tau.
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Academic Article
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Vitamin D and Vitamin K Concentrations in Human Brain Tissue Are Influenced by Freezer Storage Time: The Memory and Aging Project.
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Single cell RNA sequencing of human microglia uncovers a subset associated with Alzheimer's disease.
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Early Selective Vulnerability of the CA2 Hippocampal Subfield in Primary Age-Related Tauopathy.
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A cortical immune network map identifies distinct microglial transcriptional programs associated with ?-amyloid and Tau pathologies.
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Regional brain iron associated with deterioration in Alzheimer's disease: A large cohort study and theoretical significance.
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Academic Article
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What is 'Alzheimer's disease'? The neuropathological heterogeneity of clinically defined Alzheimer's dementia.
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Limbic-predominant age-related TDP-43 encephalopathy neuropathologic change and microvascular pathologies in community-dwelling older persons.
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Academic Article
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Proteomic identification of select protein variants of the SNARE interactome associated with cognitive reserve in a large community sample.
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Academic Article
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To what degree is late life cognitive decline driven by age-related neuropathologies?
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Association of Hemoglobin A1C With TDP-43 Pathology in Community-Based Elders.
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PLD3 is a neuronal lysosomal phospholipase D associated with ?-amyloid plaques and cognitive function in Alzheimer's disease.
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Academic Article
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Late-Life Vascular Risk Score in Association With Postmortem Cerebrovascular Disease Brain Pathologies.
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Brain insulin signaling and cerebrovascular disease in human postmortem brain.
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Academic Article
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Disrupted Rest-Activity Rhythms and Cerebral Small Vessel Disease Pathology in Older Adults.
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Academic Article
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Tripartite Relationship Among Synaptic, Amyloid, and Tau Proteins: An In Vivo and Postmortem Study.
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Cortical proteins may provide motor resilience in older adults.
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Synaptic proteins associated with cognitive performance and neuropathology in older humans revealed by multiplexed fractionated proteomics.
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B and T Lymphocyte Densities Remain Stable With Age in Human Cortex.
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The "cognitive clock": A novel indicator of brain health.
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A Genetic Study of Cerebral Atherosclerosis Reveals Novel Associations with NTNG1 and CNOT3.
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Association of Lewy Bodies With Age-Related Clinical Characteristics in Black and White Decedents.
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The association of epigenetic clocks in brain tissue with brain pathologies and common aging phenotypes.
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Academic Article
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Physical activity, brain tissue microstructure, and cognition in older adults.
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Academic Article
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Off-label use of aducanumab for cerebral amyloid angiopathy.
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Academic Article
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ARTS: A novel In-vivo classifier of arteriolosclerosis for the older adult brain.
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MIND Diet, Common Brain Pathologies, and Cognition in Community-Dwelling Older Adults.
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Association of Amyloid-? Pathology with Decision Making and Scam Susceptibility.
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Academic Article
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Analysis of genes (TMEM106B, GRN, ABCC9, KCNMB2, and APOE) implicated in risk for LATE-NC and hippocampal sclerosis provides pathogenetic insights: a retrospective genetic association study.
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The association of Lewy bodies with limbic-predominant age-related TDP-43 encephalopathy neuropathologic changes and their role in cognition and Alzheimer's dementia in older persons.
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Complex Profiles of Cerebrovascular Disease Pathologies in the Aging Brain and Their Relationship With Cognitive Decline.
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Longitudinal cognitive performance of Alzheimer's disease neuropathological subtypes.
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Brain ?-Amyloid Links the Association of Change in Body Mass Index With Cognitive Decline in Community-Dwelling Older Adults.
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Alzheimer's Disease-Related Dementias Summit 2019: National Research Priorities for the Investigation of Traumatic Brain Injury as a Risk Factor for Alzheimer's Disease and Related Dementias.
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Genome-wide association study and functional validation implicates JADE1 in tauopathy.
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Association of White Matter Hyperintensities With Pathology and Progression of Parkinsonism in Aging.
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Academic Article
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Retraction: 24-Hour Rhythms of DNA Methylation and Their Relation with Rhythms of RNA Expression in the Human Dorsolateral Prefrontal Cortex.
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Human Brain and Blood N-Glycome Profiling in Alzheimer's Disease and Alzheimer's Disease-Related Dementias.
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Academic Article
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Microglial Correlates of Late Life Physical Activity: Relationship with Synaptic and Cognitive Aging in Older Adults.
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Academic Article
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Association between WWOX/MAF variants and dementia-related neuropathologic endophenotypes.
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Academic Article
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Dementia and autopsy-verified causes of death in racially-diverse older Brazilians.
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Academic Article
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Neuropathologic Correlates of Human Cortical Proteins in Alzheimer Disease and Related Dementias.
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Academic Article
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Neuropathology of Vascular Brain Health: Insights From Ex Vivo Magnetic Resonance Imaging-Histopathology Studies in Cerebral Small Vessel Disease.
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Academic Article
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Co-expression network analysis of frontal cortex during the progression of Alzheimer's disease.
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Academic Article
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Vasculocentric Axonal NfH in Small Vessel Disease.
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Academic Article
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Brain microRNAs are associated with variation in cognitive trajectory in advanced age.
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Academic Article
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Genome-wide association study of brain arteriolosclerosis.
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Academic Article
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Genetic Evidence Supporting a Causal Role of Depression in Alzheimer's Disease.
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Cortical Proteins and Individual Differences in Cognitive Resilience in Older Adults.
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Academic Article
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Progranulin mutations in clinical and neuropathological Alzheimer's disease.
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Academic Article
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Association of Statins With Cerebral Atherosclerosis and Incident Parkinsonism in Older Adults.
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Academic Article
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Caffeine Consumption and Dementia: Are Lewy Bodies the Link?
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Academic Article
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Blood-brain barrier link to human cognitive impairment and Alzheimer's Disease.
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Association of vitamin K with cognitive decline and neuropathology in community-dwelling older persons.
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Academic Article
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Association of Traumatic Brain Injury With and Without Loss of Consciousness With Neuropathologic Outcomes in Community-Dwelling Older Persons.
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Academic Article
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Sex differences in the genetic architecture of cognitive resilience to Alzheimer's disease.
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Academic Article
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FMNL2 regulates gliovascular interactions and is associated with vascular risk factors and cerebrovascular pathology in Alzheimer's disease.
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Academic Article
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Neurodegenerative and Cerebrovascular Brain Pathologies Are Differentially Associated With Declining Grip Strength and Gait In Older Adults.
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Academic Article
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Neuropathology of Dementia Disorders.
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Academic Article
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Pelargonidin and Berry Intake Association with Alzheimer's Disease Neuropathology: A Community-Based Study.
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Academic Article
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Limbic-predominant age-related TDP-43 encephalopathy neuropathological change (LATE-NC) is associated with lower R2 relaxation rate: an ex-vivo MRI and pathology investigation.
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Bulk and Single-Nucleus Transcriptomics Highlight Intra-Telencephalic and Somatostatin Neurons in Alzheimer's Disease.
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Cerebral amyloid angiopathy interacts with neuritic amyloid plaques to promote tau and cognitive decline.
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LDL cholesterol is associated with higher AD neuropathology burden independent of APOE.
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Adherence to MIND Diet, Genetic Susceptibility, and Incident Dementia in Three US Cohorts.
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Relative Contributions of Mixed Pathologies to Cognitive and Functional Symptoms in Brain Donors Exposed to Repetitive Head Impacts.
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High-throughput digital quantification of Alzheimer disease pathology and associated infrastructure in large autopsy studies.
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Longitudinal change in serial position scores in older adults with entorhinal and hippocampal neuropathologies.
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Vesicular Glutamate Transporter Changes in the Cortical Default Mode Network During the Clinical and Pathological Progression of Alzheimer's Disease.
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When Alzheimer's is LATE: Why Does it Matter?
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Neuropathologic correlates of cerebral microbleeds in community-based older adults.
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Ex vivo MRI facilitates localization of cerebral microbleeds of different ages during neuropathology assessment.
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Cell-type-specific Alzheimer's disease polygenic risk scores are associated with distinct disease processes in Alzheimer's disease.
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Association of Mediterranean-DASH Intervention for Neurodegenerative Delay and Mediterranean Diets With Alzheimer Disease Pathology.
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Multi-omic characterization of brain changes in the vascular endothelial growth factor family during aging and Alzheimer's disease.
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Sex differences in associations between APOE e2 and longitudinal cognitive decline.
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Plasma p-tau181 and p-tau217 in discriminating PART, AD and other key neuropathologies in older adults.
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Neuropathology of the Common Forms of Dementia.
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Association of Dietary Intake of Flavonols With Changes in Global Cognition and Several Cognitive Abilities.
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The Caribbean-Hispanic Alzheimer's disease brain transcriptome reveals ancestry-specific disease mechanisms.
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Brain and spinal cord arteriolosclerosis and its associations with cerebrovascular disease risk factors in community-dwelling older adults.
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Arachnoid granulations are lymphatic conduits that communicate with bone marrow and dura-arachnoid stroma.
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Brain vitamin D forms, cognitive decline, and neuropathology in community-dwelling older adults.
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LATE-NC staging in routine neuropathologic diagnosis: an update.
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Brain autopsies of critically ill COVID-19 patients demonstrate heterogeneous profile of acute vascular injury, inflammation and age-linked chronic brain diseases.
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The MIND diet, brain transcriptomic alterations, and dementia.
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Associations of Sex, Race, and Apolipoprotein E Alleles With Multiple Domains of Cognition Among Older Adults.
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Effects of Cerebrovascular and Lewy Body Pathology on Parkinsonian Signs in Community-Dwelling Older Adults.
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Multi-Site Cross-Site Inter-Rater and Test-Retest Reliability and Construct Validity of the MarkVCID White Matter Hyperintensity Growth and Regression Protocol.
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Limbic-predominant age-related TDP43 encephalopathy (LATE) neuropathological change in neurodegenerative diseases.
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Relation of Motor Impairments to Neuropathologic Changes of Limbic-Predominant Age-Related TDP-43 Encephalopathy in Older Adults.
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TDP-43 Pathology in the Setting of Intermediate and High Alzheimer's Disease Neuropathologic Changes: A Preliminary Evaluation Across Ethnoracial Groups.
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The Boston criteria version 2.0 for cerebral amyloid angiopathy: a multicentre, retrospective, MRI-neuropathology diagnostic accuracy study.
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The status of digital pathology and associated infrastructure within Alzheimer's Disease Centers.
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Estrogen Receptor Genes, Cognitive Decline, and Alzheimer Disease.
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Trends in Postmortem Neurodegenerative and Cerebrovascular Neuropathologies Over 25 Years.
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RNASE6 is a novel modifier of APOE-e4 effects on cognition.
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Multiple gene variants linked to Alzheimer's-type clinical dementia via GWAS are also associated with non-Alzheimer's neuropathologic entities.
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Brain copper may protect from cognitive decline and Alzheimer's disease pathology: a community-based study.
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Frequency and Underlying Pathology of Pure Vascular Cognitive Impairment.
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Association of Stroke and Cerebrovascular Pathologies With Scam Susceptibility in Older Adults.
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Vascular pathology and pathogenesis of cognitive impairment and dementia in older adults.
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The association of MIND diet with cognitive resilience to neuropathologies.
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Primacy and recency effects in verbal memory are differentially associated with post-mortem frontal cortex p-tau 217 and 202 levels in a mixed sample of community-dwelling older adults.
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Multi-ancestry genome-wide meta-analysis of 56,241 individuals identifies LRRC4C, LHX5-AS1 and nominates ancestry-specific loci PTPRK , GRB14 , and KIAA0825 as novel risk loci for Alzheimer's disease: the Alzheimer's Disease Genetics Consortium.
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Age-related and amyloid-beta-independent tau deposition and its downstream effects.
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Associations of VGF with Neuropathologies and Cognitive Health in Older Adults.
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Association of AK4 Protein From Stem Cell-Derived Neurons With Cognitive Reserve: An Autopsy Study.
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The unique effect of TDP-43 on hippocampal subfield morphometry and cognition.
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Associations of cortical SPP1 and ITGAX with cognition and common neuropathologies in older adults.
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Selective serotonin reuptake inhibitor use, age-related neuropathology and cognition in late-life.
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Global Odds Model with Proportional Odds and Trend Odds Applied to Gross and Microscopic Brain Infarcts.
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Sex-specific genetic architecture of late-life memory performance.
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Longitudinal change in memory performance as a strong endophenotype for Alzheimer's disease.
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Author Correction: Central role for PICALM in amyloid-? blood-brain barrier transcytosis and clearance.
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Cell-type-specific Alzheimer's disease polygenic risk scores are associated with distinct disease processes in Alzheimer's disease.
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Cerebral Small Vessel Disease, Hypertension, and Vascular Contributions to Cognitive Impairment and Dementia.
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Sensitivity and Specificity of the Boston Criteria Version 2.0 for the Diagnosis of Cerebral Amyloid Angiopathy in a Community-Based Sample.
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Proteome-wide Analyses Identified Cortical Proteins Associated With Resilience for Varied Cognitive Abilities.
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Novel avenues of tau research.
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Concept
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Cognitive Aging
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Concept
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Neuropathology
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Concept
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Machine Learning
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Concept
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Brain Injuries, Traumatic
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Concept
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Glycogen Synthase Kinase 3 beta
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Concept
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Phosphatidylinositol-3,4,5-Trisphosphate 5-Phosphatases
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Concept
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RNA Splicing Factors
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Concept
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NIMA-Interacting Peptidylprolyl Isomerase
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Concept
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Dietary Approaches To Stop Hypertension
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Concept
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Triggering Receptor Expressed on Myeloid Cells-1
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Concept
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Netrins
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